@article {azizah_2-homoectoine_2023,
	title = {2-Homoectoine: An Additional Member of the Ectoine Family from Phyto- and Bacterioplankton Involved in Osmoadaptation},
	journal = {Journal of Natural Products},
	year = {2023},
	note = {Publisher: American Chemical Society},
	month = {dec},
	abstract = {Ectoine is a central osmolyte in marine plankton due to its excellent cytoprotective traits and its multifunctional roles supporting the survival of microalgae and bacteria under unfavorable environmental conditions. The protective effect of ectoine toward several kinds of stresses stirred interest in biotechnology, pharmacy, and other fields including cosmetics. Also, its hydroxylated derivative, 5-hydroxyectoine, exhibits functions similar to ectoine. Here we introduce a molecular networking-based approach to expand the family of ectoine derivatives from phyto- and bacterioplankton. A ZIC-HILIC separation protocol coupled with HRMS/MS-based molecular networking allowed us to identify the new ectoine derivative 1,4,5,6-tetrahydro-2-ethyl-4-pyrimidinecarboxylic acid, or 2-homoectoine (1). 1 is found in many algae including dinoflagellates, chlorophytes, and haptophytes. In axenic strains, the content of 1 is substantially lower. In accordance, we found that marine bacteria are prolific producers of the compound as well. This suggests that the microalgae with their associated microbiome have to be considered as sources of the compound. Increasing concentrations of the compound under high salinity suggest a role as a protectant against osmotic stress.},
	keywords = {RCC131, RCC3579},
	issn = {0163-3864},
	doi = {10.1021/acs.jnatprod.3c00766},
	url = {https://doi.org/10.1021/acs.jnatprod.3c00766},
	author = {Azizah, Muhaiminatul and Pohnert, Georg}
}
@article {barbosa_microalga_2023,
	title = {The microalga \textit{Dunaliella and its applications: a review},
	journal = {Applied Phycology},
	volume = {4},
	number = {1},
	year = {2023},
	pages = {99{\textendash}120},
	keywords = {RCC3579, RCC5},
	issn = {2638-8081},
	doi = {10.1080/26388081.2023.2222318},
	url = {https://www.tandfonline.com/doi/full/10.1080/26388081.2023.2222318},
	author = {Barbosa, Miguel and In{\'a}cio, Leonardo Garcia and Afonso, Cl{\'e}lia and Maranh{\~a}o, Paulo}
}
@article {Iglesias2019,
	title = {NMR characterization and evaluation of antibacterial and antiobiofilm activity of organic extracts from stationary phase batch cultures of five marine microalgae (Dunaliella sp., D. salina, Chaetoceros calcitrans, C. gracilis and Tisochrysis lutea)},
	journal = {Phytochemistry},
	volume = {164},
	number = {April},
	year = {2019},
	note = {Publisher: Elsevier tex.mendeley-tags: RCC1349,RCC1811,RCC3579,RCC5,RCC5953},
	month = {aug},
	pages = {192{\textendash}205},
	keywords = {Antibacterial, Antibiofilm, Chaetoceros, Dunaliella, Metabolite identification, NMR, RCC1349, RCC1811, RCC3579, RCC5, RCC5953, Tisochrysis},
	issn = {00319422},
	doi = {10.1016/j.phytochem.2019.05.001},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0031942219300184},
	author = {Iglesias, Ma Jos{\'e} and Soengas, Raquel and Probert, Ian and Guilloud, Emilie and Gourvil, Priscillia and Mehiri, Mohamed and L{\'o}pez, Yuly and Cepas, Virginio and Guti{\'e}rrez-del-R{\'\i}o, Ignacio and Redondo-Blanco, Sa{\'u}l and Villar, Claudio J. and Lomb{\'o}, Felipe and Soto, Sara and Ortiz, Fernando L{\'o}pez}
}
